Final answer:
Extreme pH values can indeed interfere with the flocculation process in water treatment by altering the charge balance that is essential for effective coagulation and particle binding.
Step-by-step explanation:
The statement that extreme values of pH can interfere with flocculation is True. In the water treatment process, flocculation involves the addition of chemicals with a positive charge to neutralize the negative charge of dissolved particles in the water. If the pH is too high or too low, it can alter the charge of these particles and thus negatively affect the efficiency of flocculation. For example, using alum and lime in water treatment will lead to a change in pH. An optimal pH range is necessary to ensure good coagulation and flocculation.