Final answer:
Corticosteroids and splenectomy are used in ITP treatment to suppress the immune system, reducing platelet destruction and clearance, thus increasing platelet count.
Step-by-step explanation:
Corticosteroids and splenectomy are useful in the treatment of Immune Thrombocytopenic Purpura (ITP) because they help suppress the immune system. In ITP, the immune system mistakenly attacks and destroys platelets, which are critical for blood clotting. Corticosteroids work by reducing inflammation and immune responses, thereby decreasing the destruction of platelets. A splenectomy, the surgical removal of the spleen, is sometimes necessary because the spleen is involved in the removal of platelets from the body in ITP. By taking out the spleen, you reduce the clearance of platelets, which can help increase the platelet count.
Corticosteroids and splenectomy are useful in the treatment of ITP because they suppress the immune system. In ITP, the immune system mistakenly destroys platelets, leading to low platelet counts. Corticosteroids reduce inflammation and decrease the activity of the immune system, which helps prevent platelet destruction. Splenectomy removes the spleen, which is a major site of platelet destruction in ITP.