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"What is the receptor for vWF and for thrombin?

a) P2Y12
b) GPIIb/IIIa
c) PAR-1
d) GP1b"

1 Answer

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Final answer:

The receptor for vWF is GP1b, essential for platelet adhesion during clot formation, while the receptor for thrombin is PAR-1, which activates platelets contributing to clot stabilization.

Step-by-step explanation:

The receptors for von Willebrand factor (vWF) and thrombin are important for blood clotting processes. The receptor for vWF is GP1b, which is part of the GP1b-IX-V complex on the surface of platelets. This receptor is crucial for the adhesion of platelets to damaged vascular surfaces, a key initial step in the formation of a blood clot. On the other hand, the receptor for thrombin is PAR-1 (Protease-Activated Receptor 1), which belongs to the family of G-protein-coupled receptors. This receptor plays a major role in platelet activation which leads to a conformational change in the platelet shape and the release of granules that promote further platelet activation and clot stabilization.

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