Final answer:
St. John's Wort interacts adversely with paroxetine, an antidepressant medication used to treat depression.
Step-by-step explanation:
The nurse should advise the client that St. John's Wort interacts adversely with paroxetine, an antidepressant medication often used to treat depression. St. John's Wort is an herbal supplement that can cause a drug interaction with paroxetine by decreasing its effectiveness.
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