Final answer:
The correct instruction is to prime the desmopressin nasal spray before each use. It is not related to mealtime, fluid intake restriction, or monitoring hyperglycemia.
Step-by-step explanation:
The correct instruction for a client who has diabetes insipidus and is prescribed desmopressin nasal spray is to prime the nasal spray before each use. Desmopressin is a synthetic analog of the antidiuretic hormone (ADH), which is used to treat diabetes insipidus by reducing urine production and helping to control increased thirst and urination associated with this condition.
The nurse should instruct the patient on how to prime the nasal spray correctly, as per the medication's instructions, to ensure proper dosing and effectiveness of the treatment. It is not typically advised to administer this medication with meals or to limit fluid intake drastically without medical guidance. Monitoring for signs of hyperglycemia is generally connected with diabetes mellitus and insulin use, not diabetes insipidus and ADH therapy.