Final answer:
The hypodermis, also known as subcutaneous tissue, is the layer beneath the dermis that anchors the skin to underlying structures.
Step-by-step explanation:
The layer located directly beneath (deep to) the dermis of the skin responsible for anchoring the skin to the underlying structures is the hypodermis. Also known as the subcutaneous tissue, the hypodermis connects the dermis to underlying fascia of bones and muscles. It is a layer of connective tissue that connects the dermis to the underlying fascia of bones and muscles. The hypodermis also contains adipose tissue for fat storage and protection. It consists of well-vascularized, loose, areolar connective tissue and adipose tissue, functioning in fat storage, insulation, and cushioning for the integument.