Final answer:
The year 1496 is when the war between the Zapotecs and the Aztecs gave way to peace, marked by the signing of a peace treaty.
Step-by-step explanation:
The war between the Zapotecs and the Aztecs transitioned to a state of peace in the year 1496. This transition happened with the signing of a peace treaty between the two cultures, shortly after the destructive events of 1494 when the Aztecs destroyed Zapotec capital cities. Although the timeline also mentions other significant events, such as the Spanish conquest and the Aztecs suffering a defeat at the hands of the Spanish, leading to Tenochtitlán's fall in 1521, it's the 1496 peace treaty that specifically marks the end of hostility and the establishment of peace between the Zapotecs and Aztecs.