Final answer:
The Middle Colonies were most distinctive from the other regions with regard to the diversity of the population.
Step-by-step explanation:
The Middle Colonies were most distinctive from the other regions with regard to the diversity of the population. According to historian Jack P. Greene, the middle colonies had high levels of individual competitiveness and public contention, but this diversity helped the colonists develop a pragmatic, accommodative, and tolerant approach to one another. The region had higher levels of ethnic and religious diversity compared to their northern and southern neighbors.