Final answer:
The most significant difference between the Truman Doctrine and the Eisenhower Doctrine was that the United States later believed that military aid to countries threatened by communism was no longer necessary.
Step-by-step explanation:
The most significant difference between the Truman Doctrine and the Eisenhower Doctrine was that the United States later believed e) Economic aid to countries threatened by communism was no longer necessary.
The Truman Doctrine, introduced in 1947, aimed to provide military aid to resist the spread of communism, particularly in Greece and Turkey. In contrast, the Eisenhower Doctrine, proclaimed in 1957, focused on using military force to defend Middle Eastern governments threatened by communism. Therefore, the United States' belief in the necessity of military aid rather than economic aid was the key difference between the two doctrines.