Final answer:
The combination of temperature 27°C and a pH of 4 is most likely to support the growth of acidophilic bacteria.
Step-by-step explanation:
Acidophilic bacteria are microorganisms that grow best in acidic conditions. From the given options, the combination of temperature 27°C and a pH of 4 is most likely to support the growth of acidophilic bacteria. Acidophiles have optimal growth at pH values near 3.0, and a pH of 4 is closer to their preferred range compared to the other options. The other temperature and pH combinations are either in the neutrophile or alkaliphile range, making them less supportive of acidophilic bacterial growth.