Final answer:
Europe was most impacted by the Black Death due to its high mortality rates, preceding adversities, and dense trade networks that facilitated disease spread.
Step-by-step explanation:
The area most impacted by the Black Death is widely regarded to be Europe. Several factors contributed to the harsh effects experienced there. Firstly, the densely populated areas and the poor living conditions made it easier for the disease to spread and for mortality rates to be higher.
Secondly, Europe faced adversities like drastic climate changes, rebellions, and crop failures before the plague, weakening the population's resilience. Thirdly, European societies at the time were intricately connected through trade with other regions, facilitating the spread of the disease along international routes.
The mortality rate, estimated to be between 40% to 60% of the population, alongside the subsequent economic and social upheaval, underscores the heavy toll on Europe. The Black Death's impact was variable and shaped by geographical, social, and institutional factors across different regions.