Final answer:
The "spirit of party" warned against by George Washington contributed to the deterioration of relationships between Adams and Jefferson, as well as Burr and Hamilton.
Step-by-step explanation:
The "spirit of party," as warned against by George Washington, contributed to the deterioration of the relationships between John Adams and Thomas Jefferson, as well as Aaron Burr and Alexander Hamilton. The emergence of political divisions and the formation of political parties created tension and animosity between these individuals. The Federalist and Republican parties, led by Adams and Jefferson respectively, held vastly different ideologies and policies which further fueled conflict and strained their relationships. Additionally, personal and ideological differences, such as Burr's resentment towards Hamilton, exacerbated the deterioration of their relationships.