Final answer:
Christopher Columbus did not successfully establish a new Western trade route to the riches of the Asian Orient; this is the statement among the options that is not true of his voyages. He believed he had reached Asia but did not. Columbus' voyages led to significant interactions between the Eastern and Western Hemispheres, commonly referred to as the Columbian Exchange.
Step-by-step explanation:
All of the following are true of Christopher Columbus' voyages EXCEPT: His voyage led to the "bridging" of the Eastern Hemisphere and Western Hemisphere, He is credited with being the first person to label the Native Americans as 'Indians', His voyages led to the enslavement of many indigenous peoples of the Caribbean, and His request for money for financing was rejected by all European countries except Spain. The statement that is not true of Columbus' voyages is that he successfully established a new Western trade route to riches of the Asian Orient. Although Columbus did establish routes between Europe and the Americas, he never reached the Asian Orient. He mistakenly believed he had reached Asia and called the native Taínos he encountered 'Indios', leading to the term 'Indian' for native peoples of the New World.
The Columbian Exchange followed Columbus' voyages, introducing new crops and animals to both the Old and New Worlds, but also bringing diseases to the indigenous populations. Columbus sought financial backing from several European countries but was ultimately supported by Spain, where King Ferdinand and Queen Isabella financed his expedition after initial rejections. While Columbus never achieved his initial goal of finding a new trade route to Asia, his voyages did have a profound impact on world history, leading to the colonization of the Americas and altering global economic and social structures.