Final answer:
The nucleolus's inability to function would lead to improper formation of ribosomes, affecting the rough endoplasmic reticulum and protein synthesis, and hindering lysosomal function. Similarly, without an endoplasmic reticulum, a liver cell could not metabolize toxins effectively.
Step-by-step explanation:
If the nucleolus were not able to carry out its function, it would affect several other cellular organelles. The nucleolus plays a critical role in the synthesis and assembly of ribosomes, which are crucial for protein synthesis. Without a functioning nucleolus, ribosomes would not form properly, thereby impacting free ribosomes and the rough endoplasmic reticulum (RER), which houses ribosomes on its surface. The synthesis of proteins on the RER, including enzymes needed for various cellular processes such as lysosomal enzyme creation, would be hindered. As a result, lysosomes would not have the necessary hydrolases to break down molecules, which would lead to cellular dysfunction.
By extension, a human liver cell lacking endoplasmic reticulum would struggle to metabolize toxins. The endoplasmic reticulum, particularly the smooth endoplasmic reticulum, contains enzymes needed for detoxifying harmful substances. Lacking this organelle would compromise the liver cell's ability to process and neutralize toxins, which is a vital function in preventing damage to the body.