Final answer:
Andrew Jackson's policies most significantly restricted the rights of Native Americans through the Indian Removal Act and his defiance of a Supreme Court ruling that favored the Cherokee Nation. Option c,
Step-by-step explanation:
Andrew Jackson's policies most severely restricted the rights of Native Americans.
One of his most infamous actions was the signing of the Indian Removal Act of 1830, which led to the forced relocation of Native American tribes from their ancestral homelands in the Southeastern United States to territory west of the Mississippi River (known as the Trail of Tears).
In addition to this forced removal, Jackson defied a Supreme Court ruling that recognized the rights of the Cherokee Nation, indicating a refusal to protect Native American interests. This action greatly restricted the rights and sovereignty of Native American tribes.
Throughout history, there have been systemic efforts to limit the voting rights and civil liberties of various groups. For example, African Americans faced significant challenges, such as Jim Crow laws and voting disenfranchisement tactics, preventing them from exercising their civil rights.
However, during Jackson's presidency, it was the Native Americans who were most directly and forcefully affected by his policies.
So option c is correct answer.