Final answer:
Domestication allowed for the development of agriculture and the domestication of animals, creating settled agriculture and pastoralism. These new ways of living had a profound impact on human history.
Step-by-step explanation:
The significance of domestication to mankind is that it allowed for the development of agriculture and the domestication of animals, which in turn created two new ways of living: settled agriculture and pastoralism. Settled agriculture involved cultivating crops in permanent gardens, while pastoralism involved breeding and herding animals for resources. These new ways of living had a profound impact on the course of human history by facilitating the growth of larger populations, the development of specialized occupations, the establishment of trade, and the formation of towns and cities.