Final answer:
During B cell development, the pre-B cell receptors do not receive signals from self-antigens for lymphocyte survival and proliferation.
Step-by-step explanation:
The statement that during B cell development, pre-B-cell receptors receive signals from self-antigens for the lymphocytes to survive and proliferate is false.
In reality, during B cell development, the pre-B cell receptors undergo a process of positive selection to ensure that they have normal functional receptors. Negative selection is then used to eliminate self-reacting B cells to prevent autoimmunity.
Self-reacting B cells can be eliminated through processes such as apoptosis, editing of receptors, or induction of anergy.