Final answer:
Orthopnea is the clinical manifestation not associated with right-sided heart failure. It is related to left-sided heart failure and involves difficulty breathing when lying flat.
Step-by-step explanation:
The clinical manifestation that is NOT associated with right-sided heart failure is Orthopnea. Orthopnea is typically associated with left-sided heart failure and refers to shortness of breath that occurs when lying flat, forcing the person to have to prop up or sit up to breathe comfortably. Conversely, clinical manifestations like ascites (fluid accumulation in the abdominal cavity), dependent edema (swelling of lower body parts due to gravity), and hepatomegaly (enlarged liver) are commonly seen in right-sided heart failure, as this condition leads to systemic venous congestion.
Ascites, dependent edema, and hepatomegaly are, however, associated with right-sided heart failure.