Final Answer:
B. Prolonged prothrombin time (PT) and excessive bleeding. is a common hematological (blood) feature associated with chronic liver disease.
Step-by-step explanation:
Chronic liver disease often leads to impaired synthesis of clotting factors, including those dependent on vitamin K, resulting in a B.prolonged prothrombin time (PT) and a tendency for excessive bleeding. The liver plays a crucial role in synthesizing clotting factors, and its dysfunction in chronic liver disease disrupts the delicate balance between procoagulant and anticoagulant factors.
Firstly, normal fibrinolysis (Option A) is not a common feature associated with chronic liver disease. Secondly, lymphocytosis (Option C) refers to an increase in lymphocyte count, which is not a direct hematological manifestation of liver disease. Thirdly, vitamin C deficiency (Option D) primarily affects collagen synthesis but is not a characteristic hematological feature of chronic liver disease. Lastly, the normal blood levels and activity profiles of vitamin K-dependent factors (Option E) would not be expected in chronic liver disease due to the liver's central role in synthesizing these factors.
In summary, the prolonged PT and increased bleeding tendency observed in chronic liver disease are indicative of compromised hemostatic function. This understanding is crucial in the clinical management of patients with liver disease, guiding therapeutic interventions to address the associated coagulopathies and minimize the risk of bleeding complications.