Question

Which cells destroy infected cells using perforins and granzymes?

A. natural killer cells
B. B cells
C. cytotoxic t cells
D. both A and C destroy infected cells with perforins and granzymes
E. All of the above destroy infected cells with perforins and granzymes

Answer 1

Natural killer cells and cytotoxic T cells are responsible for destroying infected cells using perforins and granzymes, making option D the correct answer.

Step-by-step explanation:

The cells that destroy infected cells using perforins and granzymes are natural killer cells and cytotoxic T cells. The correct answer is D) both A and C destroy infected cells with perforins and granzymes. Natural killer (NK) cells are always active and can recognize and kill cells showing signs of infection or tumor cells by secreting perforin, which forms pores in the target cell's membrane, and granzymes, which are proteases that enter through the perforin-created pores to trigger apoptosis.

Cytotoxic T cells are another type of cell that utilizes a similar approach; once they bind to an infected cell through antigen presentation with MHC I, they release perforin and granzymes to induce apoptosis.