Question

In general, platelet dysfunction is usually a problem with platelet aggregationthe platelet count is normal, and there is no alteration in the ability to produce platelets. In the uremic environment, however, the platelets do not promote ________________ well.

Answer 1

Platelets in the uremic environment struggle with blood clotting due to disrupted function, leading to poor hemostasis despite a normal platelet count.

Step-by-step explanation:

In the uremic environment, platelets do not promote hemostasis well due to a disruption in their function, even though the platelet count is normal.

Uremia adversely affects platelet function by interfering with the platelets' ability to stick together and form a successful clot, leading to issues with blood clotting.

The correct answer to the question is that in the uremic environment, platelets do not promote hemostasis effectively.

Platelets, or thrombocytes, are vital for blood clotting or coagulation, which changes blood from a liquid to a gel and forms a plug in a damaged blood vessel.

When platelets do not function properly, as in the case of uremic patients, there is a higher susceptibility to excessive bleeding from even minor wounds.

This dysfunction can often be attributed to factors such as a deficiency in clotting factors, but not, specifically, to excessive platelet production or the inadequate production of heparin.

Thrombocytopenia and thrombocytosis are conditions of too few or too many platelets, respectively, and they illustrate how the balance of platelet count is crucial for proper clotting.

Platelets are produced from megakaryocytes in response to thrombopoietin, and their primary function includes the aggregation that is necessary for clot formation.