Final answer:
Increasing blood pressure can lead to an increase in edema due to higher hydrostatic pressure forcing fluids into interstitial spaces. Systemic blood pressure above 60 mmHg is necessary for proper filtration in the kidneys.
Step-by-step explanation:
True, increasing blood pressure may result in an increase in edema. This occurs because higher blood pressure increases the hydrostatic pressure in the capillaries, which can push more fluid into the interstitial spaces, leading to swelling known as edema. Other factors contributing to edema include damage to blood vessels, decreased osmotic pressure due to a reduction in plasma proteins, and increased vascular permeability. For instance, in chronic liver diseases where plasma protein synthesis is impaired, there is a decrease in colloid osmotic pressure which can also lead to edema.
Systemic blood pressure must stay above a certain threshold, commonly considered to be around 60 mmHg, to ensure that adequate filtration occurs in the kidneys. If the blood pressure falls below this level, it can lead to insufficient filtration, which in extreme cases might contribute to organ dysfunction or failure.