Final answer:
The encounter between colonists and Native Americans had a significant impact on the Native American population, with diseases introduced by the Europeans causing devastating consequences.
Step-by-step explanation:
One fact about the encounter between colonists and Native Americans is that the Native Americans were greatly impacted by diseases introduced by the Europeans. These diseases, such as smallpox, were new to the Native American population and had devastating effects. The lack of immunity among the Native Americans resulted in significant population decline.