Final answer:
The formation of a precipitate is a typical indicator of a chemical change, marking the production of a new substance from a chemical reaction.
Step-by-step explanation:
The indicator that typically signifies a chemical change has taken place is the formation of a precipitate. Chemical changes involve a substance being transformed into a different substance, which can be indicated by various signs. Indications of a chemical reaction include a change in color, generation of heat or light, production of gas, and the formation of a solid product known as a precipitate. Among these, the formation of a precipitate is a clear sign that a new substance, typically insoluble in the reaction mixture, has been produced.