Final answer:
The punctuation mark that should go in the underlined space is a comma (,).
Step-by-step explanation:
The punctuation mark that should go in the underlined space is a comma (,)
When she got married, Dr. Laura changed her name to James Ramirez.
The comma is used to separate the dependent clause 'When she got married' from the independent clause 'Dr. Laura changed her name to James Ramirez'.