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A drug is prescribed for a patient to take 225 mg every 12 hours for 10 days. after 12 hours about 3% of this dose is still in the body. how much of the drug is in the body right after the last dose?

User Alleus
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Final answer:

To calculate how much of the drug is in the body right after the last dose, we need to consider the half-life of the drug and the dosing interval. After 10 days, approximately 0.11 mg of the drug is still in the body.

Step-by-step explanation:

To calculate how much of the drug is in the body right after the last dose, we need to consider the half-life of the drug and the dosing interval. The half-life is the time it takes for the concentration of the drug in the body to be reduced by half. In this case, the drug has a half-life of 12 hours. After 12 hours, about 3% of the dose is still in the body, so we can assume that the concentration of the drug decreases by 97% every 12 hours.

Let's calculate the remaining dose after 10 days, or 240 hours:

Remaining dose = Initial dose * (97%)^(total hours / half-life)

Initial dose = 225 mg

Total hours = 240 hours

Half-life = 12 hours

Remaining dose = 225 mg * (0.97)^(240 / 12)

Remaining dose ≈ 225 mg * 0.00048828125 ≈ 0.10986328125 mg

Therefore, right after the last dose, approximately 0.11 mg of the drug is still in the body.

User Screwtape
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