Question

Enalapril is the prodrug that requires metabolic conversion to its active form, enalaprilat, exerting its therapeutic effects in hypertension and heart failure management.

1) True
2) False

Answer 1

The statement about Enalapril being a prodrug converted to the active form of enalaprilat for treating hypertension and heart failure is true. It works by inhibiting the ACE enzyme, preventing the formation of angiotensin II.

Step-by-step explanation:

The statement that Enalapril is the prodrug requiring metabolic conversion to its active form, enalaprilat, to exert therapeutic effects in the management of hypertension and heart failure is true. Enalaprilat is the active form of the drug that inhibits the angiotensin-converting enzyme (ACE). This inhibition prevents the conversion of angiotensin I to angiotensin II, which is a potent vasoconstrictor and contributes to increased blood pressure. By inhibiting this conversion, ACE inhibitors such as enalaprilat help manage hypertension and heart failure.