Final answer:
Dietary lipids and lipid-soluble vitamins are absorbed from the small intestine and carried in lymph fluids within chylomicrons via lacteals; their first major destination is the thoracic duct before entering the bloodstream.
Step-by-step explanation:
The macromolecule carried from the small intestine in the lymph fluids is dietary lipids, specifically triglycerides, which are reassembled into forms called chylomicrons. Alongside these are lipid-soluble vitamins such as vitamins A, D, E, and K. These substances enter the lymphatic capillaries known as lacteals. The lacteals are part of the villi that line the small intestine and are the main way that dietary fats are absorbed from the gastrointestinal tract. After absorption, the chylomicrons and vitamins are transported via the lymphatic system. The first major destination post-absorption is the thoracic duct, which then empties these nutrients into the bloodstream, where they are distributed to various cells and tissues in the body.