Final answer:
The correct method to determine if a mouse with a dominant phenotype has a homozygous or heterozygous genotype is to cross it with a mouse with a recessive phenotype.
Step-by-step explanation:
The correct answer is c. A mouse with a dominant phenotype should be crossed with a mouse with a recessive phenotype. This method allows us to determine if the mouse with the dominant phenotype is homozygous or heterozygous. When a mouse with a dominant phenotype is crossed with a mouse with a recessive phenotype, the resulting offspring will reveal the genotype of the dominant mouse. If any offspring have the recessive phenotype, it indicates that the dominant mouse is heterozygous. If all offspring have the dominant phenotype, it indicates that the dominant mouse is homozygous for the dominant allele. For example, if a black mouse with a dominant phenotype is crossed with a white mouse with a recessive phenotype, and all the offspring have black fur, it suggests that the black mouse is homozygous for the dominant allele (BB).