Final answer:
The least common denominator for this difference is 12.
Step-by-step explanation:
The least common denominator is the smallest number that can be evenly divided by all the denominators in a set. To find the least common denominator for this difference, we need to identify the common factors among the denominators given: 12, 41, and 45.
The common factors are:
Therefore, the least common denominator for this difference is 12.