Final answer:
When making an incision into the GI tract, the layers cut from outside to inside would be serosa, muscularis externa, submucosa, and mucosa.
Step-by-step explanation:
An incision into the wall of the GI (Gastrointestinal) tract would cut through four main layers. These layers, starting from the outermost layer and moving inwards, are: serosa, muscularis externa, submucosa, and mucosa. The serosa is the outermost layer and it provides protection to the GI tract. The muscularis externa is responsible for the peristaltic movement that helps to move food and waste through the digestive system. The submucosa contains nerves, blood vessels, and glands that support the surrounding tissues. Finally, the mucosa is the innermost layer that comes in direct contact with the digestive contents.