Final answer:
The word 'uprooted' conveys a connotation of significant change implying 'B. a disruption of normalcy,' which encompasses the disturbance of the family's regular life by moving to Nebraska to become homesteaders.
Step-by-step explanation:
The connotation implied with the word uprooted in the sentence "It had been a year since she and James had uprooted the family and relocated to Nebraska to become homesteaders." suggests a significant change that disrupts the normal course of life. The best option that captures the essence of this disruption is B. a disruption of normalcy. The term uprooted metaphorically expresses a situation where someone is removed from their familiar environment or origins, just as a plant would be taken out of the soil. While this change might eventually lead to a fresh beginning or necessary change, the initial implication is one of disturbance or change in the regular pattern of living. This sense of change is reinforced when juxtaposed with other elements in the text that illustrate the challenges and hardships faced by homesteaders during the period of Manifest Destiny and westward expansion.