Final answer:
SCr stands for Serum Creatinine, and it's used to evaluate kidney function through tests such as creatinine clearance, which measures the glomerular filtration rate (GFR). Conditions like kidney failure can affect creatinine levels. The formula used to calculate creatinine clearance takes into account the concentrations in both urine and plasma.
Step-by-step explanation:
In the context of Serum Creatinine, SCr stands for Serum Creatinine, which is option 1. Serum Creatinine is a waste product found in the blood that results from normal muscle breakdown. Measuring the levels of creatinine in the bloodstream is crucial as it serves as a key indicator of kidney function.
The conditions in which blood creatinine or creatinine coefficient is increased include kidney failure, where the coefficient tends to be low, and febrile diseases, where the coefficient is high. A common measurement for assessing kidney function is the creatinine clearance test, which estimates the glomerular filtration rate (GFR)—the rate at which the kidneys filter waste. This can be calculated using the creatinine clearance formula, which considers creatinine concentration in both urine and plasma:
U x V
Ccr = --------
B
This result for Creatinine clearance (CC) is often corrected for body surface area (BSA) and represented as ml/min/1.73 m² to standardize the value among individuals of varying sizes.