Final answer:
Methaqualone affects the eyes by causing constriction of the pupils, known as miosis, and can lead to blurred or dim vision, which is uncommon for most CNS depressants.
Step-by-step explanation:
The effect of Methaqualone on the eyes, unlike most CNS Depressants, is that it causes miosis, or constriction of the pupils. This is unlike phenylephrine, an adrenergic agent that causes pupil dilation or mydriasis. Miosis can lead to symptoms such as blurred or dim vision. Other signs and symptoms of Methaqualone use include headaches, nausea, vomiting, excessive secretions or sweating, muscle twitching, dyspnea, seizures, and unconsciousness. Pilocarpine, a muscarinic agonist used for eye disorders, can reverse this effect by contracting the ciliary muscle of the eye, allowing for drainage of aqueous humor and reducing intraocular pressure. In contrast, psychoactive drugs such as amphetamines impact the brain, altering mood, perceptions, thinking, and behavior, and can sometimes lead to addiction.