Final answer:
The variable region of the T cell receptor forms the pathogen-specific binding site, while the constant region anchors the molecule on the cell surface.
Step-by-step explanation:
The region of the alpha and beta chains of the T cell receptor that forms the pathogen-specific binding site is the variable region.
This region is furthest away from the T cell membrane and its amino acid sequence varies between receptors. On the other hand, the region that anchors the T cell receptor on the cell surface is the constant region. The constant region has less variation and it spans the membrane of the T cell.