Final answer:
In the absence of costimulation, recognition of antigens by naive T cells results in anergy.
Step-by-step explanation:
In the absence of costimulation, naive T cells recognize antigens through a process called anergy. Anergy is a state of nonresponsiveness to antigen stimulation. Self-reactive T cells that escape the thymus and enter the peripheral bloodstream can become anergic if they do not receive the essential co-stimulatory signal required for activation.