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T/F: allelic exclusion of TCP alpha and beta chains is effective; therefore all T cells express only one TCR on surface.

User LuAndre
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Final answer:

True. Allelic exclusion of TCP alpha and beta chains is effective, resulting in the expression of only one TCR on the surface of T cells.

Step-by-step explanation:

True. Allelic exclusion of TCP alpha and beta chains is effective, resulting in the expression of only one TCR on the surface of T cells.



The TCR (T cell receptor) is a two-chain protein receptor found on T lymphocytes that recognizes antigens. The most common and important TCRs are the alpha-beta TCRs. Each TCR consists of an alpha chain and a beta chain.



During T cell development in the thymus, genetic rearrangement occurs, leading to the generation of a diverse population of T cells with unique TCRs. This process ensures that each T cell expresses only one specific TCR on its surface, a phenomenon known as allelic exclusion.

User Shig
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