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.Prozac, among many other drugs, functions by altering neurotransmitter

levels in the brain. How does Prozac work?
A. By making serotonin-gated channel easier to open
B. By increasing the amount of serotonin released from the presynaptic neuron,
increasing the amount available in the synapses that use it
C. By blocking the reuptake of serotonin after it has been released, increasing the amount available in the synapses that use it
D. By decreasing the amount of serotonin released from the presynaptic neuron,
decreasing the amount available in the synapses that use it

User Niddro
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Final answer:

Prozac is an antidepressant that functions as a selective serotonin reuptake inhibitor (SSRI). It blocks the reuptake of serotonin, leading to increased concentrations of serotonin in the synaptic cleft and elevated mood.

Step-by-step explanation:

Prozac, a widely known antidepressant medication, functions by impacting the levels of neurotransmitters within the brain. Specifically, Prozac operates on serotonin, one of the key neurotransmitters related to mood regulation. The action Prozac takes is that of a selective serotonin reuptake inhibitor (SSRI).

Instead of increasing the release of serotonin or affecting serotonin-gated channels, Prozac's primary mechanism is to block the reuptake of serotonin after it has been released, effectively increasing the amount present in the synapses.

This blockage prevents the presynaptic neuron from reabsorbing serotonin, leading to higher concentrations in the synaptic cleft and prolonged activation of the postsynaptic neuron. This facilitates the elevation of mood, which is beneficial in the treatment of depression.

Therefore, when asked about the role of Prozac as either an agonist or antagonist for serotonin, it can be explained that Prozac is not directly acting as either. It does not bind to receptors to mimic (as an agonist) or block (as an antagonist) serotonin.

Rather, it indirectly enhances serotonin's effects by preventing its reuptake and allowing it to remain active in the synaptic cleft longer. The correct answer to the multiple-choice question provided would be: C. By blocking the reuptake of serotonin after it has been released, increasing the amount available in the synapses that use it.

User Oleg Yamin
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