Final answer:
Synaptic plasticity is largely dependent on the increase of D) Ca2+ ions in the postsynaptic cell, which initiates a signaling cascade that can lead to long-term potentiation (LTP) or long-term depression (LTD) of the synapse. Hence, D) is correct.
Step-by-step explanation:
Synaptic plasticity is largely dependent on the increase of Ca2+ ions in the postsynaptic cell. When an action potential reaches the axon terminals, voltage-gated Ca2+ channels open, allowing Ca2+ ions to enter the cell.
The increase in Ca2+ concentration initiates a signaling cascade that can lead to long-term potentiation (LTP) or long-term depression (LTD) of the synapse, which are forms of synaptic plasticity.