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Which factor of RNA polymerase III contains a zinc finger DNA binding domain?

User Cory Shay
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Final answer:

The factor of RNA polymerase III that contains a zinc finger DNA-binding domain is known as TFIIIA. It is a subunit of the transcription factor complex that helps RNA polymerase III to initiate the transcription of small RNA molecules by recognizing and binding to specific DNA sequences.

Step-by-step explanation:

The student is asking about a specific component of RNA polymerase III that contains a zinc finger DNA-binding domain. Zinc finger domains are a common type of DNA-binding motif found in a number of transcription factors. In the context of RNA polymerase III, which is responsible for the transcription of small RNA molecules in eukaryotic cells, the factor that contains the zinc finger domain is known as TFIIIA (Transcription Factor for polymerase III A). TFIIIA is one of the multiple subunits that make up the entirety of the transcription factor complex necessary for RNA polymerase III to initiate transcription of target genes. The zinc finger domain in TFIIIA allows the protein to recognize and bind to specific DNA sequences, aiding in the accurate positioning of RNA polymerase III on the DNA template for efficient transcription.

User Aless Hosry
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