Final answer:
Long non-coding RNAs (lncRNAs) can regulate gene expression through cis actions on genes close to where they are transcribed or through trans actions on distant genes, potentially influencing cancer progression.
Step-by-step explanation:
How lncRNAs Act in Terms of Cis/Trans Regulation :
Long non-coding RNAs (lncRNAs) are a class of eukaryotic RNAs that play crucial roles in regulating gene expression. lncRNAs act in both cis and trans regard by interacting with DNA, RNA, or protein. When operating in a cis manner, lncRNAs affect the expression of genes located on the same chromosome from which the lncRNAs themselves are transcribed.
Alternatively, when acting in a trans manner, lncRNAs influence gene expression of distant genes, which can be on different chromosomes. Certain lncRNAs have been implicated in various diseases, including cancer, where their dysregulation can alter gene expression patterns, potentially leading to cancer progression.