Final answer:
The Illumina/Solexa version of massive parallel sequencing involves synthesizing DNA fragments on individual beads and determining the order of nucleotides by recording flashes of light emitted when nucleotides are incorporated in the sequence.
Step-by-step explanation:
The basic idea behind the Illumina/Solexa version of massive parallel sequencing is to use a method called synthesis sequencing, where DNA fragments are first immobilized on beads and then amplified using PCR. Each bead is placed in a separate well containing sequencing enzymes and the four nucleotides are added one by one. As each nucleotide is incorporated, pyrophosphate is released, emitting a small flash of light that is recorded by a detector. This allows the order of nucleotides to be determined and the DNA sequence to be generated quickly and efficiently.