Final answer:
To initiate an energetically favorable reaction, one can supply energy to reactants, ensure sufficient activation energy, utilize catalysts, or increase the reactants' surface area.
Step-by-step explanation:
To make an energetically favorable reaction occur, several strategies can be employed. Providing energy to reactant particles increases their vibrational frequency, making chemical bonds more likely to break upon collision, leading to reactions. Ensuring that reacting particles have enough activation energy is crucial, as some reactions only proceed at higher temperatures.
Utilizing catalysts can also accelerate the process by offering an alternative reaction pathway with lower activation energy, which is especially important in biological systems where conditions such as body temperature and pH are relatively constant. Additionally, increasing the surface area for reaction, such as using kindling instead of large logs in a fire, can enhance the rate at which the reaction occurs.