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How do Bcl2 proteins and cytochrome c interact? Is this process extrinsic or intrinsic?

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Final answer:

Bcl2 proteins play a crucial role in the release of cytochrome c from the mitochondria during apoptosis. This interaction is an intrinsic process.

Step-by-step explanation:

During apoptosis, cytochrome c is released from the mitochondria into the cytoplasm. In this process, Bcl2 proteins play a crucial role. Bcl2 proteins, such as Bak and Bax, are outer mitochondrial membrane channel components that allow the release of cytochrome c. When these proteins are signaled, they initiate the release of cytochrome c from the mitochondria, leading to molecular events that trigger apoptosis.

The interaction between Bcl2 proteins and cytochrome c is an intrinsic process. Intrinsic apoptosis is initiated by internal signals within the cell, such as DNA damage or developmental cues. In the case of cytochrome c release, it is triggered by the presence of activated Bcl2 proteins.

User Dimitris Fousteris
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