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Bcl2 overexpression (amplification) is frequently observed in cancers, therby preventing apoptosis. T/F?

User Kathryn
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Final answer:

True. Bcl2 overexpression is frequently observed in cancers and prevents apoptosis.

Step-by-step explanation:

True. Bcl2 gene overexpression is frequently observed in cancers, and it is known to prevent apoptosis, the process of programmed cell death. Bcl2 belongs to a family of proteins that regulate the intrinsic pathway of apoptosis.

These proteins inhibit the release of cytochrome C from mitochondria, which is necessary for initiating apoptosis. Therefore, overexpression of Bcl2 can block apoptosis and contribute to the survival and proliferation of cancer cells.

User Geesu
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