Question

Some transcription factors assemble onto ____ ____ prior to polymerase binding.

Answer 1

The transcription factors assemble onto the promoter DNA sequence prior to polymerase binding. Basal transcription factors, which start with 'TFII', systematically fall into place on the DNA template, stabilizing the pre-initiation complex and recruiting RNA polymerase II for transcription initiation.

Step-by-step explanation:

The transcription factors assemble onto the promoter DNA sequence prior to polymerase binding. In eukaryotes, a complex of transcription factors called basal transcription factors, which start with 'TFII', binds to the promoter of a protein coding gene. These factors systematically fall into place on the DNA template, stabilizing the pre-initiation complex and recruiting RNA polymerase II for transcription initiation.