Final answer:
During transcriptional control of gene expression, molecules can bind to regulatory sequences in DNA such as enhancers or silencers. Binding to enhancers can turn on or increase gene transcription, while binding to silencers can down-regulate or suppress gene transcription.
Step-by-step explanation:
During transcriptional control of gene expression, molecules can also bind to regulatory sequences in DNA such as enhancers or silencers. These regulatory sequences can be relatively short DNA sequences that lie close to the transcription start site of a gene or far from it in the case of eukaryotes. Binding of molecules to these regulatory sequences can turn on or increase gene transcription (enhancers) or down-regulate or suppress gene transcription (silencers).