Question

Shifts in the conformation after binding cause an _ between enzyme and the substrate.

_ bonds of the substrate are strained.

Answer 1

According to the induced-fit model, there is a conformational change in both the enzyme and the substrate when the substrate binds to the enzyme. This change in shape strains the active site and distorts the substrate, resulting in strained bonds. The induced-fit model explains how enzymes undergo dynamic conformational changes, increasing the rate of the reaction.

Step-by-step explanation:

According to the induced-fit model, when a substrate binds to an enzyme, there is a conformational change that occurs in both the enzyme and the substrate. This change in shape of the active site of the enzyme strains the shape of the active site and distorts the substrate. As a result, the bonds of the substrate are strained, making it more favorable for the reaction to occur. The induced-fit model explains how enzymes undergo dynamic conformational changes upon binding, increasing the rate of the reaction.