Final answer:
When a missing protein completes a complex in transcription regulation, it can activate gene expression.
Step-by-step explanation:
When a single missing protein is added and completes a complex, it can have different effects depending on the specific context. In the case of transcription regulation, completing a complex can lead to the activation of gene expression.
For example, if a regulatory protein was missing and unable to bind to a cis-regulatory element, the addition of that missing protein can restore the binding and activate the gene, resulting in transcription and the production of RNA.