Final answer:
The rearrangement of immunoglobulin genes by site-specific recombination and specific splicing generates a diverse repertoire of antibody molecules with unique variable regions capable of binding different antigens.
Step-by-step explanation:
The rearrangement of immunoglobulin genes by site-specific recombination followed by specific splicing of the primary transcript generates a diverse repertoire of antibody molecules with unique variable regions capable of binding different antigens.
During the maturation of certain stem cells in the bone marrow, V, D, and J regions linked to a C region recombine to create a variety of V-D-J-C immunoglobulin antibody molecules. These rearrangements occur in response to foreign substances called antigens.
The process involves the excision of V and J segments from the light chain gene in germ-line B cells, followed by splicing and RNA processing to produce unique variable chains for each differentiated B cell.